Is the Diagnosis of Acute Posterior Multifocal Placoid Pigment Epitheliopathy with Fatal Cerebral Stroke Correct? A Case Report

Aim: To reiterate the fatal cerebral stroke in association with acute posterior multifocal placoid pigment epitheliopathy (AMPEE).

Report of a Case: A previously healthy 9-year-old girl developed acute visual loss in her left eye and was diagnosed to have unilateral acute posterior multifocal placoid pigment epitheliopathy (AMPEE) elsewhere and received systemic steroid treatment with topical steroid drops. She was seen a month later by us as no visual improvement was noted by the family. The patient was hospitalized for a routine systemic work-up as the diagnosis seemed unconvincing. Three days after the hospitalization, she suffered a cerebral stroke and died in the hospital despite extensive treatment in the intensive care unit.

Conclusion: The neurologic changes including cerebral stroke can be seen in cases with AMPEE and high suspicion should be present in clinicians whenever a case with AMPEE diagnosed.