In-vivo Study of the Efficacy of Sanjeevani Vati in Snake Venom Poisoining

S. Mohurle, Pradip and Lambat, Rajendra (2021) In-vivo Study of the Efficacy of Sanjeevani Vati in Snake Venom Poisoining. Journal of Pharmaceutical Research International, 33 (50A). pp. 47-54. ISSN 2456-9119

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Abstract

Background: Visha (Poison) is a substance, which after entering the body, disturbs natural and physiological functions of body (i.e. Dosha, Dhatu, Mala). Due to its potency, it may potentially cause death in a relatively short period. A significant proportion of Indians live in villages distant from the city and work in agriculture with their lower extremities exposed. Snake-rat habitat is more prevalent in rice and sugarcane fields.

Aims and Objective: To study the efficacy of Sanjeevani Vati in common cobra venom poisoning and Russell’s viper venom as a first aid measure.

Materials and Methods: The preparation of Sanjeevani Vatiis carried out in Department of Rasashastra, Govt. Ayurved College, Nagpur and venom was collected from snake farm’, Haffkine Institute for Training Research and Testing, Mumbai. Animal Experiment for efficacy of Sanjeevani Vati as a first aid measure on Common cobra venom and Russell’s viper venom was carried out in National Toxicology Center (NTC) Pune.

Results: The results of survival period in Russell’s viper venom group were proved to be statistically significant. P value is 0.0055(Unpaired t-test; Two tail).But in results of Common Cobra venom, it was observed that there is no delay in appearance of paralysis, convulsion & survival period. In fact all these symptoms appear near about at same time, when Sanjeevani Vati was given orally after ingestion of Cobra Venom.

Conclusion: Sanjeevani Vati property is an ophidian. If you have Russell's viper venom, it is helpful as a first aid measure since it extends its life time. Poly Valent Anti snake venom serum does not interact with it (PVASVS).

Item Type: Article
Subjects: STM Digital Press > Medical Science
Depositing User: Unnamed user with email support@stmdigipress.com
Date Deposited: 01 Apr 2023 07:35
Last Modified: 23 May 2024 07:09
URI: http://publications.articalerewriter.com/id/eprint/87

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