Khordadmehr, Monireh and Matin, Reyhaneh and Baradaran, Behzad and Baghbanzadeh, Amir and Jigari-Asl, Farinaz and Katiraee, Farzad (2021) A review of the targeting sites and biological roles of miR-4800; a novel tumor biomarker with therapeutic potential. Pharmaceutical Sciences, 28 (3). pp. 376-382. ISSN 1735-403X
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Abstract
MicroRNAs (miRNAs) are known as a group of short noncoding ribonucleic acids (ncRNAs). Mainly, they can manage gene expression at the posttranscriptional level in the essential biological and physiological functions. Significantly, more than 50% of the discovered miRNAs genes are placed in cancer‐related genomic regions, which can act as oncomiR or oncosuppressor. In this regard, growing evidence recently demonstrated the deregulation of miR-4800 in human cancers and non-cancerous diseases. However, little information is available on the biological roles of miR-4800 in cancer initiation, development, and progression. Here, we reviewed the targeting sites and biogenesis functions of the miR‐4800 family in physiological and pathological processes like human cancers, particularly with a particular focusing on the validated specific targets.
Item Type: | Article |
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Subjects: | STM Digital Press > Medical Science |
Depositing User: | Unnamed user with email support@stmdigipress.com |
Date Deposited: | 16 May 2023 06:56 |
Last Modified: | 19 Sep 2024 09:31 |
URI: | http://publications.articalerewriter.com/id/eprint/843 |