Genome Analysis of Lagocephalus sceleratus: Unraveling the Genomic Landscape of a Successful Invader

Danis, Theodoros and Papadogiannis, Vasileios and Tsakogiannis, Alexandros and Kristoffersen, Jon B. and Golani, Daniel and Tsaparis, Dimitris and Sterioti, Aspasia and Kasapidis, Panagiotis and Kotoulas, Georgios and Magoulas, Antonios and Tsigenopoulos, Costas S. and Manousaki, Tereza (2021) Genome Analysis of Lagocephalus sceleratus: Unraveling the Genomic Landscape of a Successful Invader. Frontiers in Genetics, 12. ISSN 1664-8021

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Abstract

The Tetraodontidae family encompasses several species which attract scientific interest in terms of their ecology and evolution. The silver-cheeked toadfish (Lagocephalus sceleratus) is a well-known “invasive sprinter” that has invaded and spread, in less than a decade, throughout the Eastern and part of the Western Mediterranean Sea from the Red Sea through the Suez Canal. In this study, we built and analysed the first near-chromosome level genome assembly of L. sceleratus and explored its evolutionary landscape. Through a phylogenomic analysis, we positioned L. sceleratus closer to T. nigroviridis, compared to other members of the family, while gene family evolution analysis revealed that genes associated with the immune response have experienced rapid expansion, providing a genetic basis for studying how L. sceleratus is able to achieve highly successful colonisation. Moreover, we found that voltage-gated sodium channel (NaV 1.4) mutations previously connected to tetrodotoxin resistance in other pufferfishes are not found in L. sceleratus, highlighting the complex evolution of this trait. The high-quality genome assembly built here is expected to set the ground for future studies on the species biology.

Item Type: Article
Subjects: STM Digital Press > Medical Science
Depositing User: Unnamed user with email support@stmdigipress.com
Date Deposited: 20 Jan 2023 08:46
Last Modified: 18 Jun 2024 07:30
URI: http://publications.articalerewriter.com/id/eprint/36

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