Evaluation of Cytotoxic Effect in Ag/ZnO Nanocomposites on Human Myelogenous Leukaemia

Lakshmi, S. Magara Jothi and Rejith, S. G. (2024) Evaluation of Cytotoxic Effect in Ag/ZnO Nanocomposites on Human Myelogenous Leukaemia. UTTAR PRADESH JOURNAL OF ZOOLOGY, 45 (12). pp. 102-113. ISSN 0256-971X

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Abstract

The Ag/ZnO nanocomposite was successfully synthesized through the co-precipitation method, as confirmed by the simultaneous presence of Ag and ZnO reflections in powder X-ray diffraction analysis, validating its formation. Analysis using FESEM revealed an average particle size of around 22 nm and displayed a unique flower-like morphology, indicating a distinctive self-assembly and growth pattern of the nanocomposite. Structural composition and functional groups were studied using FT-IR spectroscopy. The nanocomposite exhibited direct and indirect band gaps of 3.06 and 3.00 eV, respectively, determined through UV-Vis NIR spectrometry and Tauc plot analysis. Evaluation of the cytotoxic effect on K562 (human myelogenous leukaemia) cells demonstrated a concentration-dependent decrease in cell viability, highlighting the potential of the nanocomposite to induce cytotoxic effects on these cancer cells.

Item Type: Article
Subjects: STM Digital Press > Biological Science
Depositing User: Unnamed user with email support@stmdigipress.com
Date Deposited: 22 May 2024 06:56
Last Modified: 22 May 2024 06:56
URI: http://publications.articalerewriter.com/id/eprint/1409

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